Agilent 6460 Triple Quad

The Agilent 6460 Triple Quadrupole LC/MS delivers superior sensitivity for trace level analysis with performance specifications in Signal-to-Noise ratio (S/N) and Instrument Detection Limit (IDL). IDL is a rigorous, statistically based metric that indicates practical sensitivity performance of your quantitative assays. The Agilent 6460 Triple Quadrupole LC/MS achieves sensitivity and resolution specifications with autotune.

Parameter	Measure	Specification
MRM sensitivity Signal-to-Noise ratio    (S/N) ESI positive	1 pg of reserpine injected on column, quantifying on the transition m/z    609 to 195	S/N > 30,000:1 Noise 1 x RMS
MRM sensitivity Signal-to-Noise ratio    (S/N) ESI negative	1 pg of chloramphenicol injected on column, quantifying on the transition    m/z 321 to 152	S/N > 10,000:1 Noise 1 x RMS
MRM sensitivity Instrument Detection    Limit (IDL) ESI positive	20 fg of reserpine injected on column, quantifying on the transition m/z    609 to 195	IDL < 12.5 fg
MRM sensitivity Instrument Detection    Limit (IDL) ESI negative	20 fg of chloramphenicol injected on column, quantifying on the    transition m/z 321 to 152	IDL < 12.5 fg
Mass range m/z		5 - 3,000
Polarity switching		30 ms
Mass resolution (autotune)	Full width at half maximum	0.7 Da
Mass resolution (manual tune)	Full width at half maximum	0.5 Da
Mass accuracy		0.1 Da from 5 - 1,000 m/z
		0.01% from 1,000 - 2,000 m/z
		0.02% from 2,000 - 3,000 m/z
Mass stability		< 0.1 Da in 24 h
Dynamic range		> 6.0 x 106
Scan modes		MS scan, MS/MS product ion scan, MRM, MS/MS neutral loss/gain scan and    precursor ion scan, SIM
Maximum scan rate		12,500 Da/s
Minimum MRM dwell time		1 ms
MRM transitions		450 per time segment > 40,000 ion transactions per method
Dynamic MRM transitions		4,000 ion transitions per method
Triggered MRM transitions		Up to 10 MRM transitions (primary and secondary) for library search and    compound confirmation
Collision cell ion clearance		< 1 ms

Single-point data system method capability with full control of Agilent 1200 Series HPLC systems and 6460C Triple Quadrupole LC/MS System

• Polarity change in time segmentScan and SIM or MRM (plus other modes of data collection)
• Dynamic and triggered MRM aligns MRMs with compound retention time
• Solvent divert through calibrant delivery system valve

Wide range of ionization sources

• Electrospray (ESI)Nanospray with HPLC-Chip Cube MS interface
• APCI source (Atmospheric Pressure Chemical Ionization)
• Multimode source (simultaneous ESI and APCI)
• APPI source (Atmospheric Pressure Photo Ionization)

Autotune

Solvent declustering
Countercurrent gas

High-energy conversion dynode and high-gain electron multiplier horn

Two turbomolecular pumps with one mechanical pump

KRSS Ltd offer high quality pre-owned Mass Spec, LCMS, GCMS, HPLC and GC systems allowing affordable entry into a rapidly developing market.

All KRSS instruments are thoroughly inspected by ex-manufacturer or KRSS trained engineers (including all components and parts), cleaned and decontaminated, completely refurbished (defective parts and components are replaced with genuine parts), serviced and bench tested to ensure the equipment meets our Used | Refurbished | KRSS Approved specifications - this guarantees quality, performance and reliability at a fraction of the OEM costs.

With over 50 instruments in stock, covering all major manufacturers KRSS has systems for a variety of application requirements. All instruments are supplied with a comprehensive warranty and optional service contracts to ensure trouble free operation.